{"id":16989,"date":"2014-05-05T13:37:54","date_gmt":"2014-05-05T13:37:54","guid":{"rendered":"https:\/\/nexplasmagen.com\/facts\/"},"modified":"2022-12-23T16:56:47","modified_gmt":"2022-12-23T16:56:47","slug":"faits","status":"publish","type":"page","link":"https:\/\/nexplasmagen.com\/fr\/faits\/","title":{"rendered":"Faits"},"content":{"rendered":"

[vc_row css_animation=\u00a0\u00bb\u00a0\u00bb row_type=\u00a0\u00bbrow\u00a0\u00bb use_row_as_full_screen_section=\u00a0\u00bbno\u00a0\u00bb type=\u00a0\u00bbgrid\u00a0\u00bb angled_section=\u00a0\u00bbno\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb background_image_as_pattern=\u00a0\u00bbwithout_pattern\u00a0\u00bb padding_top=\u00a0\u00bb80″ padding_bottom=\u00a0\u00bb0″ anchor=\u00a0\u00bbportfolio\u00a0\u00bb background_color=\u00a0\u00bb#ffffff\u00a0\u00bb][vc_column][vc_row_inner row_type=\u00a0\u00bbrow\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb css_animation=\u00a0\u00bb\u00a0\u00bb][vc_column_inner width=\u00a0\u00bb1\/3″]

\"R\u00e9cidive

R\u00e9cidive du cancer de sein<\/h3><\/span>Dans le monde, plus d’un million de femmes subissent chaque ann\u00e9e une chirurgie conservatrice du sein comme traitement. Les avantages de la combinaison de la radioth\u00e9rapie apr\u00e8s une lumpectomie chirurgicale locale ont d\u00e9montr\u00e9 de meilleurs r\u00e9sultats avec un taux de r\u00e9cidive locale r\u00e9duit.<\/span><\/p>\n

 <\/p>\n

N\u00e9anmoins, on signale un taux de r\u00e9cidive locor\u00e9gionale du cancer du sein de 15 % dans les 10 ans<\/span><\/span><\/a>,<\/span><\/span> sans compter les pr\u00e9occupations fr\u00e9quemment soulev\u00e9es quant \u00e0 l’\u00e9tat de la marge pathologique apr\u00e8s une tumorectomie. Dans les deux cas, la mastectomie est la proc\u00e9dure privil\u00e9gi\u00e9e, ce qui emp\u00eache les femmes de pr\u00e9server leur sein tout en augmentant la morbidit\u00e9 et le co\u00fbt des soins aux patientes.<\/span><\/div>[vc_separator type=\u00a0\u00bbtransparent\u00a0\u00bb up=\u00a0\u00bb79″ down=\u00a0\u00bb0″][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb1\/3″]

\"Chirurgie

Chirurgie augment\u00e9e par plasma froid<\/h3><\/span>La plupart des principales th\u00e9rapies anticanc\u00e9reuses, y compris les radioth\u00e9rapies et les chimioth\u00e9rapies, fonctionnent principalement par le biais du stress oxydatif cellulaire, afin de provoquer la mort des cellules canc\u00e9reuses sans affecter les tissus sains. De m\u00eame, le plasma froid est un gaz ionis\u00e9 non thermique qui g\u00e9n\u00e8re diverses esp\u00e8ces r\u00e9actives induisant un stress oxydatif cellulaire similaire.<\/span><\/p>\n

 <\/p>\n

Cependant, le plasma froid a la capacit\u00e9 unique de d\u00e9livrer ces esp\u00e8ces r\u00e9actives directement au niveau de la marge chirurgicale dans le lit de la tumeur, pendant l’op\u00e9ration, ce qui r\u00e9pond aux pr\u00e9occupations li\u00e9es aux th\u00e9rapies traditionnelles qui endommagent les organes environnants et g\u00e9n\u00e8rent des effets secondaires.<\/span><\/p>\n

 <\/p>\n

NexPlasmaGen con\u00e7oit un dispositif qui permettrait au chirurgien de tuer les cellules canc\u00e9reuses restantes, responsables des taux \u00e9lev\u00e9s de r\u00e9cidives locor\u00e9gionales.<\/span><\/div>[vc_separator type=\u00a0\u00bbtransparent\u00a0\u00bb up=\u00a0\u00bb30″ down=\u00a0\u00bb0″][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb1\/3″]

\"Dispositif

Dispositif brevet\u00e9 \u00e0 plasma froid<\/h3><\/span>NexPlasmaGen a con\u00e7u et brevet\u00e9 un dispositif de plasma froid (US 7,608,839<\/span><\/span><\/a> et WO2021\/022371 A1) qui peut produire et d\u00e9livrer de mani\u00e8re s\u00e9lective les esp\u00e8ces de plasma les plus pertinentes pour un type de cancer donn\u00e9, afin de produire le stress oxydatif cellulaire optimal induisant la mort des cellules canc\u00e9reuses.<\/span><\/p>\n

 <\/p>\n

La conception de NexPlasmaGen est particuli\u00e8rement bien plac\u00e9e pour permettre l’effet \u00a0\u00bb th\u00e9rapeutique \u00a0\u00bb reproductible souhait\u00e9 dans le traitement des cancers, puisqu’elle cr\u00e9e un environnement plasmatique contr\u00f4l\u00e9 qui ne modifie pas les propri\u00e9t\u00e9s du plasma au site de traitement.<\/span><\/div>[vc_separator type=\u00a0\u00bbtransparent\u00a0\u00bb up=\u00a0\u00bb30″ down=\u00a0\u00bb0″][\/vc_column_inner][\/vc_row_inner][vc_row_inner row_type=\u00a0\u00bbrow\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb css_animation=\u00a0\u00bb\u00a0\u00bb][vc_column_inner][vc_column_text]<\/p>\n

<\/h3>\n

Nos articles scientifiques \u00e9valu\u00e9s par des pairs et portant sur la technologie CPJ et ses versions ant\u00e9rieures:<\/span><\/h3>\n

 <\/p>\n

-Jean-S\u00e9bastien Boisvert, Julie Lafontaine, Audrey Glory, Sylvain Coulombe, et Philip Wong (2020) \u201cComparison of Three Radio-Frequency Discharge Modes on the Treatment of Breast Cancer Cells in Vitro\u201d, IEEE Transactions on radiation and plasma medical sciences, Vol.4, No.5. (lien vers l\u2019article)<\/a><\/span><\/p>\n

 <\/p>\n

– Julie Lafontaine, Jean-S\u00e9bastien Boisvert, Audrey Glory, Sylvain Coulombe, et Philip Wong (2020), \u201cSynergy between Non-Thermal Plasma with Radiation Therapy and Olaparib in a Panel of Breast Cancer Cell Lines\u201d, Cancers, 12, 348; doi:10.3390\/cancers12020348. (lien vers l\u2019article)<\/a><\/span><\/p>\n

 <\/p>\n

-Leduc M., Guay D., Leask R.L., Coulombe S. (2010). \u201cEffect of Non-Thermal Plasmas on DNA and Mammalian Cells\u201d, Plasma Proc. Poly., 7, 899-909. (lien vers l\u2019article)<\/a><\/span><\/p>\n

 <\/p>\n

-Leduc M., Guay D., Leask R.L., Coulombe S. (2009). \u201cCell Permeabilization Using a Non-Thermal Plasma\u201d, New J. of Phys., 11, 1-12. (lien vers l\u2019article)<\/a><\/span><\/p>\n

 <\/p>\n

-Leduc M., Coulombe S. et Leask R.L. (2009). \u201cAtmospheric Pressure Plasma Jet Deposition of Patterned Polymer Film for Cell Culture,\u201d IEEE Trans. Plasma Sci. (Special Issue on Atmospheric-Pressure Plasmas: Science and Applications) 37, 927-933. (lien vers l\u2019article<\/a>)<\/span><\/p>\n

 <\/p>\n

-L\u00e9veill\u00e9 V. et Coulombe S. (2006). \u201cElectrical Probe Calibration and Power Calculation for a Miniature 13.56 MHz Plasma Source\u201d, Meas. Sci. Technol. 17, 3027-3032. (lien vers l\u2019article)<\/a><\/span><\/p>\n

 <\/p>\n

-L\u00e9veill\u00e9 V. et Coulombe S. (2006). \u201cAtomic Oxygen Production and Exploration of Reaction Mechanisms in a He-O2 Atmospheric Pressure Glow Discharge Torch\u201d, Plasma Proc. Poly. 3(8), 587- 596.(lien vers l\u2019article)<\/a><\/span><\/p>\n

 <\/p>\n

-Yonson S., Coulombe S., L\u00e9veill\u00e9 V. et Leask R. L. (2006). \u201cCell Treatment and Surface Functionalization Using a Miniature Atmospheric Pressure Glow Discharge Plasma Torch,\u201d J. Phys. D: Appl. Phys. 39, 3508-3513. (lien vers l\u2019article)<\/a><\/span><\/p>\n

 <\/p>\n

-Coulombe S., L\u00e9veill\u00e9 V., Yonson S. et Leask R. (2006). \u201cMiniature Atmospheric Pressure Glow Discharge Torch (APGD-t) for Local Biomedical Applications,\u201d Pure & Applied Chemistry, 78(6), 1137-1146. (lien vers l\u2019article)<\/a><\/span><\/p>\n

 <\/p>\n

-L\u00e9veill\u00e9 V. et Coulombe S., (2005). \u201cDesign and Preliminary Characterization of a Miniature Pulsed RF APGD Torch with Downstream Injection of the Source of Reactive Species\u201d, Plasma Sources Science and Technology, 14, 467-476.(lien vers l\u2019article)<\/a><\/span>[\/vc_column_text][vc_separator type=\u00a0\u00bbtransparent\u00a0\u00bb up=\u00a0\u00bb79″ down=\u00a0\u00bb0″][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row css_animation=\u00a0\u00bb\u00a0\u00bb row_type=\u00a0\u00bbrow\u00a0\u00bb use_row_as_full_screen_section=\u00a0\u00bbno\u00a0\u00bb type=\u00a0\u00bbgrid\u00a0\u00bb angled_section=\u00a0\u00bbno\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb background_image_as_pattern=\u00a0\u00bbwithout_pattern\u00a0\u00bb padding_top=\u00a0\u00bb80″ padding_bottom=\u00a0\u00bb0″ anchor=\u00a0\u00bbportfolio\u00a0\u00bb background_color=\u00a0\u00bb#ffffff\u00a0\u00bb][vc_column][vc_row_inner row_type=\u00a0\u00bbrow\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb css_animation=\u00a0\u00bb\u00a0\u00bb][vc_column_inner width=\u00a0\u00bb1\/3″][vc_separator type=\u00a0\u00bbtransparent\u00a0\u00bb up=\u00a0\u00bb79″ down=\u00a0\u00bb0″][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb1\/3″][vc_separator type=\u00a0\u00bbtransparent\u00a0\u00bb up=\u00a0\u00bb30″ down=\u00a0\u00bb0″][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb1\/3″][vc_separator type=\u00a0\u00bbtransparent\u00a0\u00bb up=\u00a0\u00bb30″ down=\u00a0\u00bb0″][\/vc_column_inner][\/vc_row_inner][vc_row_inner row_type=\u00a0\u00bbrow\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb css_animation=\u00a0\u00bb\u00a0\u00bb][vc_column_inner][vc_column_text] Nos articles scientifiques \u00e9valu\u00e9s par des pairs et portant sur la technologie CPJ…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"full_width.php","meta":{"footnotes":""},"class_list":["post-16989","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/nexplasmagen.com\/fr\/wp-json\/wp\/v2\/pages\/16989"}],"collection":[{"href":"https:\/\/nexplasmagen.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nexplasmagen.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nexplasmagen.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nexplasmagen.com\/fr\/wp-json\/wp\/v2\/comments?post=16989"}],"version-history":[{"count":9,"href":"https:\/\/nexplasmagen.com\/fr\/wp-json\/wp\/v2\/pages\/16989\/revisions"}],"predecessor-version":[{"id":17114,"href":"https:\/\/nexplasmagen.com\/fr\/wp-json\/wp\/v2\/pages\/16989\/revisions\/17114"}],"wp:attachment":[{"href":"https:\/\/nexplasmagen.com\/fr\/wp-json\/wp\/v2\/media?parent=16989"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}